ethyl 3-amino-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate
ETHYL 5-AMINO-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE-4-CARBOXYLATE
CAS: 133922-58-4
Molecular Formula: C7H8F3N3O2
ethyl 3-amino-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate - Names and Identifiers
ethyl 3-amino-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate - Physico-chemical Properties
| Molecular Formula | C7H8F3N3O2 |
| Molar Mass | 223.1525 |
| Storage Condition | −20℃ |
ethyl 3-amino-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate - Introduction
ETHYL 5-AMINO-3-(TRIFLUOROMETHYL)-is an organic compound with the chemical formula C8H8F3N3O2. Its main properties are as follows:
1. Appearance: colorless to light yellow liquid or crystal.
2. Solubility: Soluble in common organic solvents such as ethanol, dimethylformamide and dichloromethane.
3. relative density: about 1.45g/cm³.
4. Boiling point: about 260-261°C.
ETHYL 5-AMINO-3-(TRIFLUOROMETHYL)-has the following main uses:
1. Pesticide intermediates: It can be used as intermediates for the synthesis of some pesticides, such as pyrazolone pesticides.
2. Drug intermediates: It can be used to synthesize some drugs, such as antiepileptic drugs and antitumor drugs.
3. chemical reagents: it can be used in organic synthesis reactions, such as oxidation, reduction and coupling reactions.
The method for preparing ETHYL 5-AMINO-3-(TRIFLUOROMETHYL)-is generally the following steps:
1.2-trifluoromethyl -3,5-dinitropyridine and ethyl acetate react to generate 2-trifluoromethyl -3,5-dinitropyridine acetate.
2.2-Trifluoromethyl-3, 5-dinitropyridine acetate reacts with hydrated ammonia to generate ETHYL 5-AMINO-3-(TRIFLUOROMETHYL)-benzyl.
1. Appearance: colorless to light yellow liquid or crystal.
2. Solubility: Soluble in common organic solvents such as ethanol, dimethylformamide and dichloromethane.
3. relative density: about 1.45g/cm³.
4. Boiling point: about 260-261°C.
ETHYL 5-AMINO-3-(TRIFLUOROMETHYL)-has the following main uses:
1. Pesticide intermediates: It can be used as intermediates for the synthesis of some pesticides, such as pyrazolone pesticides.
2. Drug intermediates: It can be used to synthesize some drugs, such as antiepileptic drugs and antitumor drugs.
3. chemical reagents: it can be used in organic synthesis reactions, such as oxidation, reduction and coupling reactions.
The method for preparing ETHYL 5-AMINO-3-(TRIFLUOROMETHYL)-is generally the following steps:
1.2-trifluoromethyl -3,5-dinitropyridine and ethyl acetate react to generate 2-trifluoromethyl -3,5-dinitropyridine acetate.
2.2-Trifluoromethyl-3, 5-dinitropyridine acetate reacts with hydrated ammonia to generate ETHYL 5-AMINO-3-(TRIFLUOROMETHYL)-benzyl.
Last Update：2024-04-09 02:00:50
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CAS: 133922-58-4
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CAS: 133922-58-4
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
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